The newest lab contribution is a review paper on amphibian skin peptides and their role in defense and healing published today in the journal Molecules. This paper is a collaboration with Dr. Elena Grasselli and her team and colleagues at Università degli Studi di Genova. The article reviews the many known roles of these peptides in protecting amphibians from microbes, predators, parasites, and more generally environmental insults. It emphasizes research on the documented function of some frog skin peptides as promoters of wound healing. One section discusses the role of skin peptides in inhibiting chytrid fungal growth, and in protecting frogs of some species from lethal chytridiomycosis. The sheer number and diversity of amphibian skin peptides, which is constantly being accrued by discoveries from newly sampled species, may contribute to a rich pharmacopeia of compounds benefiting human health.
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January 2023
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